The Design for Epidemiology Designathon, a collaboration between Co-Creation Hub and Facebook, aimed to support tech-enabled health startups (in Ideation or MVP stages) in Nigeria to develop innovative solutions for disease prevention, leveraging Facebook’s Data for Good. Held over three days in mid-October 2021, the event selected 12 teams from numerous applications to explore and utilize Facebook’s datasets for disease monitoring and control. Through workshops on Human-Centered Design and Facebook’s Data for Good, teams developed and pitched their solutions to a panel of judges, including representatives from Facebook, NCDC, eHealth Africa, and CcHUB. Two winning teams in the IDEA and MVP categories received $10,000 and $15,000 respectively. These teams, including D-Tracker Ltd, Myclinic Ng Ltd, Healthstack Solutions, and 9th digit Contracting Ltd, proceeded to a three-month pilot program to refine their prototypes and business models through iterative testing.